Wednesday, March 11, 2009

F4/80 Macrophages Are Elevated in BCL6 KO Mice

Wondering if this is the key to the increased Th17 differentiation in the KOs...

I had looked at CD11b+ Macs in the KO mice before, and didn't really see much increase. But F4/80+CD11b- Macs are highly increased in the spleens of KO mice. Can't find anything in the literature about F4/80+CD11b- Macs, but F4/80 is a clear Mac marker. This is definitely worth pursuing further...